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Re: flipper44 post# 4318

Tuesday, 02/11/2014 10:34:34 AM

Tuesday, February 11, 2014 10:34:34 AM

Post# of 704365
I'm not sure about seeing the word "encouraged" used prior to results being released, but I've seen it issued with the release of failed results.

Here's an example of a phase IIb trial where "no difference" was shown between the treatment and control arms, so it was a failure. But the company was "encouraged" by the secondary outcome:

http://investor.cyclacel.com/releasedetail.cfm?ReleaseID=614395

This isn't a vaccine so it isn't relevant to DCVax's odds. Nonetheless it is interesting in that it reversed the IMUC experience: this study used PFS as the primary outcome and it failed. But had they used OS it might have succeeded.
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