NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

You have a point. The only reason I added the fourth alternative is because Linda powers said the systemic response (aka: "the second stage of what [they] anticipate to see") is expected to be seen over a "much longer longer timeframe." That's why I think they are going to add the metastatic patients as the trial progresses -- in addition to the way it is listed on clinicaltrrials.gov -- which first lists local tumor then metastatic tumors.

Still Asco worthy? I think it could be, because scientists are now able to determine when a sustained immune response is detected in the lymphs and elsewhere. Plus, it would be pretty darned impressive to see an eradicated tumor in each patient (who otherwise likely had a very short time to live with no other options) plus indications of sustained immunity. Also, starting out simple (aka: individual tumor) may make more sense in "first in human" trials. Finally, DCVAX-L can't get lost in the shuffle, and so I believe the timing of Direct announcements is also critical.

Anyway, all our theories are positive and hopeful, and as you say….we shall see.