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Re: ou71764 post# 3370

Monday, 01/13/2014 9:09:44 PM

Monday, January 13, 2014 9:09:44 PM

Post# of 699732
I think your wager will result in a draw. Without looking it up myself at this moment, you sound certain on the 30% (so she probably misspoke when she said 25%), but I think any dilution would be long after the preliminary (first) patient "glimpses".

I'll take the wager in the spirit of camaraderie. I think we received more information on the overall DCVAX-L stats today. She wanted us to know they have 10 years and 200 patients (with 1000 treatments) with an 80% response rate. That is very high, and it is very helpful. (With only one….just one…possible serious adverse event -- amazing)!

Also with the above 200 patients -- including compassionate use, she stated extension of PFS and OS beyond standard of care was at least 16 months for each….which places PFS at least at 23-24 months and OS at least at 31-32 months.


This is also amazing new news because it includes compassionate use patients as well.

Have a great evening. I enjoy your posts.


P.S. I think her wording left room for her to have already actually seen glimpses of Direct results….I find this to be the case, because the wording sounds spontaneous and vague, but it is actually well thought out when closely examined. Example, 'we expect to be seeing glimpses early this year….and by golly, we are seeing them'

It makes sense to me that, at the very least, the German enrollment will start on DCVAX-L before they tell us anything about Direct patient results. I also think it is likely that they want to announce the opening of clinics for Direct in Europe prior to initial patient results here in the U.S..

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