NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

Gpb, great post.

You make some very good points. I do think great success in phase 1 may force some serious decisions regarding how best to move forward (or not) on multiple additional cancers. The funds will be there (with stellar results). Enrollment speed will be a nonissue (on inoperable tumors). If tumor regression were then picked as a primary (not secondary) endpoint….

I think they left themselves several avenues with which to move forward depending on the quality of response and rate of response. Certainly 60 patients will not get them across the finish line, but reasonable modifications could make phase 2 the pivotal trial.


It will be interesting.


I also agree NWBO is not out of the woods yet. It it biotech after all, and there is no telling until we are told.

I'll read your post again tomorrow when I have more time. I'll probably have a few more thoughts/questions.

Thanks again.

P.S. I'll go back and look at those preclinical studies again….they are very technical. I agree colorectal was otherwise a logical choice based upon your reasoning.