NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

Doktor, here's a potentially helpful animation.

It might be more likely that DCVAX-Direct will have more capacity to create Anti-PD1 antibodies. I watched a Roche video on this technology a while back….I'm a sucker for animation. Scroll down to the video section.

http://www.biooncology.com/pipeline-molecules/anti-pdl1


My conjecture back then was that since the PD-L1 biomarkers do not 'pop' up on tumors until activated by anti-tumor activity, it might be that Direct takes advantage of PD-L1 pre, concurrent and post activation structure (if at all different). Whereas DCVAX-L "nibbles" at dead tumors to uptake its biomarkers, DCVax-direct "nibbles" at live tumors.