Sunday, December 29, 2013 9:27:05 PM
Good points. I agree completely.
The immune system has clearly failed at the time the time the patient has surgery. But after surgery and the initial chemo, the cancer is at its ebb and the chemo hasn't poisoned the patient yet. It's the optimum time for the vaccine to succeed.
The patient's dendritic cells are being prepped for the vaccine outside the patient. Whatever deception the cancer has imparted to the dendritic cells that are left in the patient, the cells growing outside the patient that will be used for the vaccine aren't subject to that.
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