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Monday, 11/25/2013 8:29:38 AM

Monday, November 25, 2013 8:29:38 AM

Post# of 97239
$NVGN 6.17 pm. Novogen (NVGN) Unit Reports Strong Trilexium Data on Ovarian Cancer
Novogen Limited (Nasdaq: NVGN) reported that its US subsidiary, CanTx, has found that lead drug candidate Trilexium is highly effective at destroying ovarian cancer spheroid architecture.

Novogen Group Chief Scientific Officer, Dr David Brown, said today, “This result is a important step forward in predicting the likely success of Trilexium in vivo and in the clinic in particular. Spheroids are mini-tumors and the ability of Trilexium to penetrate and to kill these tumor cell structures is a significant step forward for this drug.”

Researchers at Yale University have shown that cancer stem cells isolated from the tumors of ovarian cancer patients are able to form self-renewing spheroids, regarded as a 3-dimensional model of ovarian cancer in the test tube. When injected into a mouse model, these spheroids form highly vascularized tumors mirroring that of the human disease.

http://bit.ly/19VYIaX

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