RNA interference : from biology to clinical applications edited by Wei-Ping Min, Thomas Ichim. Other Authors Min, Wei-Ping. Ichim, Thomas, 1976- Published New York : Humana Press, c2010. Physical Description xvi, 450 p. : ill. ; 27 cm. Series Methods in molecular biology, 1064-3745 ; 623. Springer protocols. Methods in molecular biology (Clifton, N.J.) ; v. 623. Springer protocols Subjects RNA editing. Gene silencing. RNA Interference. Contents Endogenous antiviral mechanisms of RNA interference : a comparative biology perspective /? Abubaker M.E. Sidahmed and Bruce Wilkie Monitoring innate immune recruitment by siRNAs in mammalian cells /? Michael P. Gantier and Bryan R.G. Williams Current knowledge of microRNAs and noncoding RNAs in virus-infected cells /? Dominique L. Ouellet and Patrick Provost Allele-specific silencing by RNA interference /? Hirohiko Hohjoh Computational siRNA design considering alternative splicing /? Young J. Kim Bioinformatic approaches to siRNA selection and optimization /? Pirkko Muhonen and Harry Holthofer Optimized gene silencing by co-expression of mulitple shRNAs in a single vector /? Yasuhito Ishigaki, Akihiro Nagao, and Tsukasa Matsunaga Stratiges in designing multigene expression units to downregulate HIV-1 /? Jane Zhang and John J. Rossi Designing optimal siRNA based on target site accessibility /? Ivo L. Hofacker and Hakim Tafer Chemical syntheses of 2'-O-alkylated siRNAs /? Joachim W. Engels ... [et al.] siRNA specific delivery system for targeting dendritic cells /? Xiufen Zheng ... [et al.] Hydrodynamic delivery protocols /? Piotr G. Rychahou and B. Mark Evers New methods for reverse transfection with siRNA from a solid surface /? Satoshi Fujita ... [et al.] Nonviral siRNA delivery for gene silencing in neurodegenerative diseases /? Satya Prakash, Meenakshi Malhotra, and Venkatesh Rengaswamy Using siRNA to uncover novel oncogenic signaling pathways /? Jin-Mei Lai, Chi-Ying F. Huang, and Chang-Han Chen 12 More... Notes Includes bibliographical references and index.
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