Rivulet Media Inc (fka RIVU)

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Patent Summary
(12) Patent Application: (11) CA 2612200
(54) English Title: METHOD OF CANCER TREATMENT USING SIRNA SILENCING
(54) French Title: METHODE DE TRAITEMENT DU CANCER PAR EXTINCTION GENIQUE AU MOYEN DE ARNSI

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Abstracts

English Abstract




The present invention is a method for the treatment of cancer involving tumor
derived immunosuppression in a subject. The method comprises administering to
a subject one or more siRNA constructs capable of inhibiting the expression of
an immunosuppressive molecule. The invention also provides siRNA constructs
and compositions.


French Abstract

La présente invention est une méthode pour traiter un cancer impliquant une immunosuppression dérivée de tumeur chez un sujet. La méthode comprend l'administration à un sujet d'une ou plusieurs produits d'assemblage d'ARNsi capables d'inhiber l'expression d'une molécule immunosuppressive. L'invention permet aussi d'obtenir des produits d'assemblage d'ARNsi et des compositions.



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Patent Details

(51) International Patent Classification (IPC):
A61K 31/713 (2006.01)
A61P 35/00 (2006.01)
(72) Inventors (Country):
MIN, WEI-PING (Canada)
(73) Owners (Country):
LONDON HEALTH SCIENCES CENTRE RESEARCH INC. (Canada)
(71) Applicants (Country):
LONDON HEALTH SCIENCES CENTRE RESEARCH INC. (Canada)
(74) Agent: SIM & MCBURNEY
(45) Issued:
(86) PCT Filing Date: 2006-06-15
(87) PCT Publication Date: 2006-12-21
Examination requested: 2011-06-15
(30) Availability of licence: N/A
(30) Language of filing: English
Patent Cooperation Treaty (PCT): Yes
(86) PCT Filing Number: PCT/CA2006/000984
(87) International Publication Number: WO2006/133561
(85) National Entry: 2007-12-14