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Wednesday, 06/19/2013 9:07:26 PM

Wednesday, June 19, 2013 9:07:26 PM

Post# of 426232
Vascepa or Icosapent Ethyl is an EPA Prodrug and EPA is a Prodrug for Resolvins of E class (RvE1,2,&3) the science is new and HUGE. The RvE's work at the vascular structures because this is where EPA interacts with the COX-2 enzyme. The DHA Neuroprotective "resolvins" RvD's work at the neurologic structures, eyes, brain, nerves where DHA normally interacts with the COX-2.

The EPA active metabolite Resolvins are produced by natural enzymatic reactions in the body, thus making EPA their "prodrug" by definition. It's now obvious and prior art since a dumb-ass like me found and posted this information. Amarin's IP should provide a nice base to build Resolvin RvE's off of.

The future market for Resolvins is as easy and as valuable as trying to put a price tag on the Hiawian Islands. Resolvins are the future of 21st treatments of Cancer, CVD, PVD, chronic pain, and Crohn's disease...this list is NOT all inclusive. EPA provides the base to build this science, Amarin has EPA IP until 2030.

The NIH has spent(guessing)Billions of dollars in grants advancing Resolvin science. Read:

http://www.ncbi.nlm.nih.gov/pubmed/21963090
http://www.ncbi.nlm.nih.gov/pubmed/22844113
http://www.ncbi.nlm.nih.gov/pubmed/23438748
http://www.ncbi.nlm.nih.gov/pubmed/23484005
http://www.ncbi.nlm.nih.gov/pubmed/23709617
http://www.ncbi.nlm.nih.gov/pubmed/23438740
http://www.ncbi.nlm.nih.gov/pubmed/23510485
http://www.ncbi.nlm.nih.gov/pubmed/23500003
http://www.ncbi.nlm.nih.gov/pubmed/18437155
http://www.ncbi.nlm.nih.gov/pubmed/23528855
http://www.ncbi.nlm.nih.gov/pubmed/22450811
http://www.ncbi.nlm.nih.gov/pubmed/21418190
http://www.ncbi.nlm.nih.gov/pubmed/23241890
http://www.ncbi.nlm.nih.gov/pubmed/23186989
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785519/
http://www.nidcr.nih.gov/Research/ResearchResults/ScienceBriefs/Archive/SNIB2009/November/Resolvin.htm
http://www.ncbi.nlm.nih.gov/pubmed/22449948
http://www.ncbi.nlm.nih.gov/pubmed/17114001
http://www.ncbi.nlm.nih.gov/pubmed/23430978
http://www.ncbi.nlm.nih.gov/pubmed/21255928
http://www.ncbi.nlm.nih.gov/pubmed?cmd=Link&dbFrom=PubMed&from_uid=18480426
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590122/
http://www.ncbi.nlm.nih.gov/pubmed/22013115
http://www.ncbi.nlm.nih.gov/pubmed/21206090
http://www.ncbi.nlm.nih.gov/pubmed/23462912

Any BP not watering at the mouth to own Amarin's IP would be greatly uninformed.

This is HUGE. Please link to ST, Twitter, and YMB.

Williams


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