Amarin Corp Plc (AMRN)

[Biobillionair]

It's looks like Amarin might have the structure confused too:)

Vascepa label is listed as ethyl all-cis-5,8,11,14,17-icosapentaenoate or Icosapent Ethyl the active ingrediant in the OB.
http://www.vascepa.com/full-prescribing-information.pdf

Pub Chem search has ethyl all-cis-5,8,11,14,17-icosapentaenoate listed as:

http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3298

This is NOT Icosapent Ethyl. Icosapent ethyl is:

http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=9831415

According to PubChem, an NIH site, Icosapent Ethyl is not ethyl all-cis-5,8,11,14,17-icosapentaenoate. Either Amarins label is wrong or the NIH is wrong.

It's likly the wild natural "fish oil" is one and Vascepa is the other considering the chemical treatment of fish oil to derive Vascepa.

Epadel is interestingly considered Icosapent Ethyl and likly has fueled some of the confusion.

Lovaza is considered to have "ICOSAPENT (EPA ETHYL ESTER",

http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=9831414

Confused yet?
Lovaza is likely contains EPA of "ICOSAPENT (EPA ETHYL ESTER" and Vascepa (the chemically altered isomer) ethyl all-cis-5,8,11,14,17-icosapentaenoate.

The two have the same molecular formula but chemically separate 2D and 3D structures. Epadel likely messed up and called it's drug Icosapent Ethyl and Amarin copied their homework. The correct name for both Epadel and Vascepa I suspect is "ethyl all-cis-5,8,11,14,17-icosapentaenoate" and should be corrected at the FDA website and label. Lovaza's Omega source should be listed as (4,7,10,13,16,19-Docosahexaenoic acid, ethyl ester, (4Z,7Z,10Z,13Z,16Z,19Z)-, mixt. with (5Z,8Z,11Z,14Z,17Z)-ethyl 5,8,11,14,17-eicosapentaenoate)
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=135261807

In conclusion, any way you skin it, Vascepa is a NCE...how do you like them apples shorty.

Williams