InvestorsHub Logo
Followers 234
Posts 26887
Boards Moderated 0
Alias Born 01/12/2013

Re: yoyo88 post# 6196

Monday, 05/13/2013 10:59:29 PM

Monday, May 13, 2013 10:59:29 PM

Post# of 426856
"An ester linkage", first Ethyl Esters are well Esters no slap anything on to it. LOL
Second an Ethyl was slapped on...covalently. Third, the new salt MAPP excludes Ethyl Esters.

You can't go around slapping esters onto old drugs and create new ones:

? Active moiety - The molecule or ion, excluding those appended portions of the molecule that cause the drug to be an ester,17 salt (including a salt with hydrogen or coordination bonds), or other noncovalent derivative (such as a complex, chelate, or clathrate) of the molecule, responsible for the physiological or pharmacological action of the drug substance.

If the drug is already an ester and it's covalently bonded to an Ethyl, by definition you have created a new chemical. It happens to act like an EPA prodrug, and has totally separate pharmacology when considering EPA blood levels;). NCE--yes, when---only the FDA truely can answer this.

Icosapent Ethyl is a prodrug of EPA, stated in the FDA medical review....I didn't make that up, the FDA did.

LOL, sounds like a probasher trying to create doubt. He should probable read the MAPPs r/t salts, take some organic, then get back to me.
Volume:
Day Range:
Bid:
Ask:
Last Trade Time:
Total Trades:
  • 1D
  • 1M
  • 3M
  • 6M
  • 1Y
  • 5Y
Recent AMRN News