Friday, May 03, 2013 12:58:49 AM
First... this was interesting that its stated that Dr. Brekken has an equity interest in Peregrine... which tells me he clearly sees the broad potential in Bavituximab!
Competing interests: R. A. Brekken is a consultant for, has equity interest in, and is a recipient of a sponsored research grant from Peregrine Pharmaceuticals and Affitech AS. R. A. Brekken is also an author of a patent on technology that was used to develop the antibody r84 by Peregrine Pharmaceuticals and Affitech AS. M. Nyquist-Andersen and A. Kavlie are employees of Affitech AS, and K. Schlunegger is an employee of Peregrine Pharmaceuticals, which supported these studies by providing r84, mcr84, and funding. Peregrine and Affitech did not participate in the planning, execution, or interpretation of the experiments. The authors affirm that they will adhere to the PLoS data sharing statement.
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0012031
Industry Sponsored Awards, dollar amounts not available
Anderson, Matthew, Study of FLUENCY PLUS Endovascular Stent Grant in Treatment of In-Stent Restenosis in AV Access Venous Outflow Circuit (RESCUE); Brekken, Rolf, Evaluating Biology and Therapeutic Mechanism of NEO-201 and NEO-301;
... scroll down to the "industry sponsored awards.." section
http://www.utsouthwestern.edu/newsroom/center-times/year-2012/september/grants-september-may.html
CJ... or anyone that may be familiar: This states industry sponsored awards and the only section that does not list who is awarding the grant/award... and specifically states "amounts not available"... would this be common or whomever is gifting the money can choose to keep it concealed?
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..Relevant and robust modeling of breast and pancreatic cancer are also key aspects of studies in the Brekken lab... (would like to hear him speak at ASCO 2013... time will tell!
http://txccr.org/dl/bios/Bio_RAB.pdf
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Biographical Sketch:
http://txccr.org/dl/bios/biosketches/brekken.pdf
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Synergys Biotherapeutics Scientific Advisory Board (was on with the late Dr. Thorpe)
http://www.synergysbio.com/#!scientific-advisory-board/c1xuq
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On the Supervisory Committee with the late Dr. Thorpe...
as shown:
TARGETING NANOPARTICLES TO TUMOR VASCULATURE
by Andrei M. ... just listing the acnkowledgement section as it relates to Dr. Thorpe
ACKNOWLEDGEMENTS
I would like to thank my mentor, Dr. Philip Thorpe, for supporting me and my research for the last six years. He taught me how to think as a researcher and to aim for the important findings. He tried to stimulate my imagination by always approaching me with the most unexpected questions. He tried to instill into me the most important quality of a pharmacologist: the ability to foresee a potential new drug.
I would like to thank to everybody in my lab for creating such a pleasant and productive environment to work in. Most significantly to Linda, who does everything from keeping the lab organized to remembering our birthdays; Xianming, who always has a solution for any experimental problem; and Shuzhen, for helping me with more columns and purifications than I can remember.
Last, but not least, I am thankful to Nancy McKinney in the Division of Basic Science who has provided solace on many occasions and to Karen Kazemzadeh for orchestrating the Immunology program and keeping everything on track
http://repositories.tdl.org/utswmed-ir/bitstream/handle/2152.5/288/marconescuandrei.pdf?sequence=3
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"Bavituximab is a first-in-class phosphatidylserine (PS)-targeting monoclonal antibody that is the cornerstone of a broad clinical
pipeline." -- Big Pharmas nightmare... unless they are fortunate enough to have The Bavi Edge!
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