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Re: Ubertino post# 66559

Monday, 03/11/2013 7:19:17 PM

Monday, March 11, 2013 7:19:17 PM

Post# of 146240
This I agree with. And I am not saying that we'll never have micelles that can kill bacteria. I'm just saying that the mechanism of action will be different from the current viricides, and that no development work has been done on this. Right now NNVC has to concentrate on getting Flucide out. Then it will work to get out HIVcide and other antivirals. When it's a big established company with steady revenues coming in the door they'll no doubt start looking to see if they can kill bacteria. But anybody needing a new antibiotic right now, or in the next few years, is going to be getting from somewhere other than NNVC.

When a virus attaches to a nanoviricide it conveniently destroys itself. I don't think we can assume we'll be lucky twice. Even if you get your micelle to attach to a bacterium the bacterium probably won't do us the favor of blowing up. Remember that a bacterium is a lot bigger than a virus. Most likely it will be necessary to design a micelle that can cross the bacterial cell wall and deliver a payload to its innards. All the while trying to make sure that it won't cross eukaryotic cell walls. Remember that the much touted safety of nanoviricides is due to the fact that they don't need to enter cells to work. Once you deliberately design 'cides that do enter cells, a lot of safety issues arise.
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