Inflammation

[noretreat]

All are OTC. Let's start with 3. All the summaries are lifted from Wikipedia.

Grape seed extract:
Human case reports and results from basic research provide preliminary evidence that grape seed extract may affect heart diseases such as hypertension, high levels of blood cholesterol,[1] platelet aggregation or inflammation.[2] None of these possible effects has been confirmed in vivo.

Resveratrol:
The effects of resveratrol are currently a topic of numerous animal and human studies. Its effects on the lifespan of many model organisms remain controversial, with uncertain effects in fruit flies, nematode worms,[5] and short-lived fish. In mouse and rat experiments, anticancer, anti-inflammatory, blood sugar-lowering and other beneficial cardiovascular effects of resveratrol have been reported. In humans, however, while reported effects are generally positive, resveratrol may have lesser benefits.[6] In one positive human trial, extremely high doses (3–5 g) of resveratrol, in a proprietary formulation designed to enhance its bioavailability, significantly lowered blood sugar.[7] This 28-day Phase 1b study was conducted privately in India by the pharmaceutical company, Sirtris, and was announced at an investor conference in 2008.[8] Although it has been alluded to in review articles, the study has never been published in a peer-reviewed scientific publication. Despite the mainstream press alleging resveratrol's anti-aging effects,[9] there are no accepted data to form a scientific basis for the application of these claims to mammals (see life extension section below). At the present time, research on resveratrol is in its infancy and the long-term effects of supplementation in humans are not known

Alpha Lipoic Acid:
Lipoic acid has been the subject of numerous research studies and clinical trials:
Prevent organ dysfunction[37]
Reduce endothelial dysfunction and improve albuminuria[38][39]
Treat or prevent cardiovascular disease[40]
Accelerate chronic wound healing[41]
Reduce levels of ADMA in diabetic end-stage renal disease patients on hemodialysis[42]
Management of burning mouth syndrome[43][44][45]
Reduce iron overload[46]
Treat metabolic syndrome[47][48][49]
Improve or prevent age-related cognitive dysfunction[50][51]
Prevent or slow the progression of Alzheimer’s Disease[52][53][54]
Prevent erectile dysfunction (animal models)[55][56]
Prevent migraines[57]
Treat multiple sclerosis[58][59][60]
Treat chronic diseases associated with oxidative stress[61]
Reduce inflammation[62]
Inhibit advanced glycation end products (AGE)[63]
Treat peripheral artery disease