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Re: BioInfo post# 1536

Monday, 02/11/2013 6:31:46 PM

Monday, February 11, 2013 6:31:46 PM

Post# of 691367
IMUC vs NWBO

Seems a little simplistic to me to talk about IMUC only being in ph 2 and NWBO being in ph 3. IMUC has 278 patients enrolled in their ph 2 study, whereas NWBO will have a total of 300 in their phase 3 study. If NWBO will truly not finish enrolling until Q4 2014, they will likely not have top line results until the end of 2015 - a full 2 years after IMUC has top line results. Given the number of patients in IMUC's ph 2 study, IMO it's likely that their drug will be approved if their phase 2 results are similar to their phase 1 results, simply because the phase 1 results showed such a huge improvement over the current std of care (ie, there's a pressing unmet need in the treatment of GBM, so the first drug with impressive ph 2 or ph 3 results will likely be fast tracked for approval).

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