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Thursday, 11/08/2012 11:17:57 AM

Thursday, November 08, 2012 11:17:57 AM

Post# of 346050
There is more to this APS story then what I have posted so far.
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=81225196
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=81239853
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=81241148
The research presented in last year's Ramesh et al paper and in yesterday's presentation at the AHA
meeting is an explanation of why the side-effects of using Bavi for cancer treatment have not included increased
thrombosis. If you remember when the trials first started this was a concern because of the increase
of thrombosis seen in APS and since Bavi also binds to beta2-GPI. Now we can understand at least one
of the mechanisms for why this does not happen.

Here is info on apoER2. You can see why the approach of reducing this to block the chain of events in APS is not a good idea.
http://en.wikipedia.org/wiki/ApoER2
CJ's post pulling together the pieces.
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=81227620
The Ramesh et al 2011 paper freely available:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007129/
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