Avid Bioservices Inc (CDMO)

[freethemice]

The difference in this case is that bavi is used to prevent the reduction of NO produced by the enzyme eNOS (endothelial NO synthase),
and not to increase the production of NO by macrophages. The figure below shows how bavi switches the macrophage
phenotype from M2 to M1. The M1 macrophages increase their production of NO by another form of NOS, iNOS (inducible NOS).
This figure was shown in Thorpe's NYAS symposium talk.