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Thursday, October 25, 2012 2:51:07 PM
detected during the treatment phase when the clinical responses are evaluated. Many
complete responses don't last but relapse because there are still tumor cells around
that have survived the therapy and then proliferate and are resistant to the therapy.
The only way to tell if patients have developed immunity is to wait and see if they are
cancer-free over a long period of time, free of relapse. Obviously you can't inject
tumor cells into the survivors to see if they are immune as you can with mice.
It is not true that
bavi helps the innate immune response triggered by the chemo/radiation damage, but by itself does nothing tangible because the cancer cells have learned to evade the immune cells and PS molecule is just one of several mechanisms of evasion
I suggest you listen and watch Thorpe's talk at the NY Academy of Sciences on May 1, 2012 to
learn how bavi actually works.
http://www.nyas.org/MediaPlayer.aspx?mid=25e51622-c908-46ef-bba1-95ca6a814eed
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