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Re: DewDiligence post# 150289

Tuesday, 10/09/2012 2:38:09 PM

Tuesday, October 09, 2012 2:38:09 PM

Post# of 252255
I'm not oblivious to the base rates. Every single DMD trial for AD has failed to date. But none have shown this kind of success in trials. The technology has changed a lot in the past 5 yrs (since most of current ph 3s were started) and the ability to select the right patients and ability to measure change and regulatory mindset on endpoints has vastly improved.

I also think this is a positive for gantenerumab, which is in a much better designed trial

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