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Re: ghmm post# 148046

Friday, 08/31/2012 9:37:24 PM

Friday, August 31, 2012 9:37:24 PM

Post# of 252586
There's some discussion of Ligand's drug in this presentation from a few years back (see p37):

http://www.faqs.org/sec-filings/100624/LIGAND-PHARMACEUTICALS-INC_8-K/dex991.htm#b

Oral BACE inhibitors that penetrate the blood-brain barrier have been very hard to come by despite a lot of effort.

The dramatic failure of a gamma-secretase inhibitor casts at least a shadow over this target as well.

Peter

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