Avid Bioservices Inc (CDMO)

[jonnyrocket]

In reply to my own question, I found this- though my questioon is if they go from CR to PR...at what point can we say we had a CR, and can that change - for example, we had CR's at the time of unblinding data and data collection, though we now have no CR's...etc. etc.

Complete Response (CR): Complete response means all detectable tumor has disappeared. If a treatment does cure some patients, those patients will have their tumor disappear. A CR is a potential cure. If you have advanced cancer a CR is also the best result you can actually see from treatment. Even so, a complete response does not necessarily mean the patient is cured. Even when no tumor can be seen on scans, there can be residual tumor which is too small to detect, and so unfortunately, complete responses may not last. Whether a complete response is likely to last can often be gauged by looking at the history of the type of treatment that produced the response in your type of cancer. In some situations very few complete responses are cures and in others most are cures. To find out, you have to research your cancer and the treatment in question.

A patient who has had a complete response may be said to be "NED". NED means "No Evidence of Disease".