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genisi

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genisi

Re: zipjet post# 132626

Thursday, 12/08/2011 2:22:26 PM

Thursday, December 08, 2011 2:22:26 PM

Post# of 253533
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Cabozantinib inhibited osteoclast activity as assessed by serum NTx, a marker of bone resorption.

Interesting that cabo shows activity in two different osteotropic cancers - breast cancer metastases are usually osteolytic, and prostate cancer metastases are usually osteoblastic.
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