A couple things I have learned during some of these prior PDUFA plays (e.g. POZN, AVNR, DEPO), is that during the drama (i.e. bear raids, shelf filings, partnership disputes), adding shares on the dips or on the plummet is the way to go....and holding your core shares too. I'm not going to lie, it's hard to do and it's painful watching it. However, if you are true to your DD and you get the approval, it's all worth it. I also found that you need to be prepared for anything and know what you plan to do if it happens. For example, now if there is a partnership dispute prior to approval, I'll know how to react vs. sitting there thinking, what the heck just happened and what should I do. For PLX, I want to be prepared for any possible drama, since the drama seems endless on these plays.
All of the above/below is in my opinion only. Please do not buy or sell based on what I have written.