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Re: Dew post# 37043

Thursday, 09/02/2010 11:33:19 AM

Thursday, September 02, 2010 11:33:19 AM

Post# of 105534
Dew, is CBAI.OB involved with Celgene Placenta research? I look forward to your response.

International Stem Cell Meeting Reports Pluripotent Stem Cells Isolated From Placenta Ethically Non-Controversial Stem Cells Can Be Obtained from Placenta

SAN DIEGO, April 13 /PRNewswire-FirstCall/ -- Celgene Corporation (Nasdaq: CELG) announced that human placenta-derived stem cells that are "*pluripotent" *thx dianebRN, or have the ability to become different types of tissue, can be isolated with a proprietary perfusion technology from placentas so they are available for potential treatment applications, according to an oral presentation yesterday at the International Conference on Stem Cells Research and Therapeutics in San Diego by Qian Ye, PhD, Senior Scientist, at Celgene Cellular Therapeutics.

"This study contributes to a growing body of evidence that the placenta is an important and novel source of stem cells that can potentially be used for the repair of damaged or diseased tissue," said Robert Hariri, President of LifebankUSA and Celgene Cellular Therapeutics.

The objective of the study was to use a proprietary perfusion method to recover pluripotent stem cells from human placenta after birth, culture them, and characterize the cells from a surface marker and differentiation perspective. The study used human placentas that were donated to LifebankUSA following the birth of normal, full-term pregnancies. Through a unique proprietary process that anatomically perfuses the placenta, mononucleated cells were obtained, purified, and cultured. Fluorescence activated cell sorter (FACS) analysis was used for cell surface marker characterization, and reverse transcription polymerase chain reaction (RT-PCR) for gene expression analysis.

Within two to four weeks, adherent cells with fibroblast-like morphology could be grown from the placenta perfusate culture. Morphologic examination and quantitative gene analysis showed that these cells express morphologic features and a gene transcript that are the hallmark of primitive stem cells. Under certain culture conditions, these cells were transformed into cartilage- like and fat-like tissue.

Celgene Cellular Therapeutics first reported that it had isolated placental stem cells and turned them into nerve, blood, cartilage, skin and muscle cells in 2001. Since that time, other studies have confirmed that pluripotent and multipotent placental and cord blood stem cells can be isolated. The study presented yesterday employed a proprietary placenta perfusion method to recover the cells from placentas after birth.

"Demonstrating the full potential of the stem cells recovered by this novel method provides Celgene scientists with another opportunity to further stem cell research and the stem cell therapy development process," said Dr. Hariri.

About Potential of Cellular Therapies

There are many disorders and diseases that are caused by the destruction of human tissue or the disruption of cellular function. Although donated tissues and organs can be used to replace the tissue in some diseases, the need far exceeds the number of organs available. Stem cell therapy has the potential to treat and cure conditions such as heart disease, Parkinson's disease, Alzheimer's disease, stroke, burns, autoimmune disorders, diabetes and arthritis. Human embryos were once thought to be the only source of stem cells that could give rise to all types of tissue, but several studies have shown that stem cells derived from the placenta following birth may have similar regenerative abilities.

About Celgene Cellular Therapeutics

Celgene Cellular Therapeutics, a wholly-owned subsidiary of Celgene Corporation, is a biotherapeutics company pioneering the development of stem cell therapies and biomaterials derived from human placental tissue. CCT has developed proprietary technology for collecting, processing and storing placental stem cells with potentially broad therapeutic applications in cancer, as well as autoimmune, cardiovascular, neurological, and degenerative diseases.

About LifebankUSA

LifebankUSA, a business unit of Celgene Cellular Therapeutics, is one of the world's top private umbilical cord blood banks, providing services for thousands of families worldwide since 1998. The number of units stored at its cryobanking facilities, which are located in Cedar Knolls, New Jersey, and Baton Rouge, Louisiana, is approaching 20,000. It is the only private bank with two fully-equipped facilities that are both ISO certified and accredited by the American Association of Blood Banks, and its comprehensive research operation is one of the largest in the cord blood banking industry. For more information, please visit the LifebankUSA website at http://www.lifebankusa.com.

About Celgene

Celgene Corporation, headquartered in Summit, New Jersey, is an integrated global biopharmaceutical company engaged primarily in the discovery, development and commercialization of innovative therapies for the treatment of cancer and inflammatory diseases through gene and protein regulation. For more information, please visit the Company's website at http://www.celgene.com.

This release contains certain forward-looking statements which involve known and unknown risks, delays, uncertainties and other factors not under the Company's control, which may cause actual results, performance or achievements of the Company to be materially different from the results, performance or other expectations implied by these forward-looking statements. These factors include results of current or pending research and development activities, actions by the FDA and other regulatory authorities, and those factors detailed in the Company's filings with the Securities and Exchange Commission such as 10K, 10Q and 8K reports.

CONTACT:
Robert J. Hugin
Senior VP and CFO
+1-908-673-9102 begin_of_the_skype_highlighting +1-908-673-9102 end_of_the_skype_highlighting

Brian P. Gill
Director, PR/IR
+1-908-673-9530 begin_of_the_skype_highlighting +1-908-673-9530 end_of_the_skype_highlighting
Both of Celgene Corporation

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I see where you got mistaken; #5 FamilyCord with 15k in storage is not #3 LifeBankUSA owned by Celgene.

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How are we processing placenta without Celgene's blessing or do we process it for Celgene?
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In Nov 2002, LifebankUSA was acquired by Celgene (Nasdaq: CELG) , a globally integrated biopharmaceutical company that recognized the potential of LifebankUSA’s placental and cord blood stem cell platform. LifebankUSA’s parent company, Celgene, invests heavily in research and development in order to set the standard for the therapeutic use of stem cells. LifebankUSA continues to operate at the NJ laboratory.

The former CEO and CFO of Corcell founded LifeBankUSA prior to it being acquired by Celgene.
http://parentsguidecordblood.org/content/usa/research/industry.shtml

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Celgene matches the CBR Alere info mofnc provided in terms of global territory.

mofnc, thx and let me know if this works on the overlay. It is very similar: http://www.celgene.com/about-celgene/celgene-locations-map.aspx


Here Mr Long, put it together.

www.alere.com/en/worldwide-locations.html



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