Rivulet Media Inc (fka RIVU)

[Buell]

Good Read

http://www.centerwatch.com/clinical-trials/results/new-therapies/nmt-details.aspx?CatID=44

These guys are in PhaseII. Osiris stock looks to be a nice play. I've done a little DD (not that I'm going to buy) but they have something coming off Phase III that the military wants.


Osiris released positive interim results from a phase II trial of Prochymal stem cell therapy for the treatment of chronic obstructive pulmonary disease (COPD). This double-blind, placebo-controlled study enrolled 62 subjects with moderate to severe COPD. The subjects were randomized to receive four infusions of either Prochymal or placebo, both with standard of care, and will be followed for two years. The endpoints are improvements based on pulmonary function tests, exercise capability, and quality of life. These data are from six months following initial infusion. Prochymal significantly decreased the levels of inflammation, as measured by C-reactive protein (CRP) compared to placebo in subjects with elevated CRP (>4 mg/L) at the time of study entry (p<0.05). The difference from placebo was evident at ten days post initial infusion, and was maintained throughout the treatment and follow-up period. However, pulmonary function tests such as forced expiratory volume in one second (FEV1) were not improved over placebo following treatment with Prochymal at six months. All subjects completed the planned course of four infusions without any evidence of infusional toxicity and adverse events were comparable between the two arms.

anyway good luck to all.
B