Treating critical limb ischemia with stem cells would be monumental! CLI is a major cause of leg amputations that results in mortality withing five years after surgery. Diabetics in their late stages more than likely develop CLI. There is an early stage in diabetics called neuropathy that decreases nerve sensation in their feet. Neuropathy then results in callouses that cause repetitive microtrauma, then ulcers.
As the article states, diagnosing Peripheral Vascular Disease (PVD) may be done by a stethoscope. However, a more precise test commonly used is called an arterial doppler. On a physical examination, advanced PVD would show no hair growth on the toes, feet and legs because of lack of nourishment to them.
Not only as a patient advocate, medical professional, and CBAI shareholder, In 2005, there were more than 80,000 amputations related to critical limb ischemia. I am thrilled by the advances that await us on treating this disease.
GTLA
