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Re: steveporsche post# 5613

Friday, 04/11/2008 7:45:24 AM

Friday, April 11, 2008 7:45:24 AM

Post# of 12660
My simulations took into account the timing of enrollees. As I indicated in the previous post, the trial will achieve stat sig about 50% of the time if the trigger was 240 and D9901+02a assumed as the model. But you also need to think through issues about the health of early patients and also of late patients as deviations from D9901+02a. Early simulations seem to indicate that the chance would be better, not worse.

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