GTC Biotherapeutics (fka GTCB)

[cellzc]

As a molecular biologist, I have to say sth about this. glycosylation is a way cells modify proteins. in higher order organisms, most of proteins are glycosylated in order to function properly. The reason that they need to genetically modified yeast is because yeast is quite different from human cells and they dont glycosylate proteins in the same way as human cells do. But if a protein is expressed in transgenic goat, pig or whatever mammals, it should been glycosylated (or modified) in the same way as it's in human cells. So no yeast can beat this. They use yeast just because it's easier to culture, not because it gives better protein.
The BOTTOM LINE is this "glycosylation in genetically modified yeast" is not as fancy as it sounds. and it can't produce proteins better than a transgenic animal.