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io_io

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io_io

Re: iwfal post# 4982

Saturday, 11/10/2007 2:32:52 PM

Saturday, November 10, 2007 2:32:52 PM

Post# of 12660
"I think CEGE’s CEO is just playing word games by saying that the interim analysis will be based on the HR"......"Agreed".


The HR is a property of the Drug. The p value is not.

The CEO knows only his Drug, has asked his statistician for the HR threshold for success, and has been told.

The same thing happens in every trial. In fact the statistical designer first asks what kind of HR can the drug achieve.

"....on the biotech battle-field, you need some élan...."

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