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Re: drbio45 post# 562

Wednesday, 07/04/2007 7:39:33 PM

Wednesday, July 04, 2007 7:39:33 PM

Post# of 9810
The evidence is that with Orbec there will be perhaps an extra 10%-15% more long-term survivors from these stem-cell transplant procedures. If not, they will die.

Here's a July 4th special, it'a a 2003 paper from Germany, people can download the PDF in the top right corner.

http://jco.ascopubs.org/cgi/content/full/21/14/2747

It's in non-myeloablatives for CLL. The paper concludes:


However, of greater concern than the acute chemotherapy-related toxicity after HSCT is the morbidity and mortality caused by acute and chronic GVHD. Despite intensification of GVHD prophylaxis by the combination of CS with short-course MTX or MMF, GVHD still remained the major problem.

And:

This was particularly true for patients with unrelated donors.*

(* where Orbec showed something like a HR of 9.0 in a sub-group analysis)


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