PCES - In fact, not many people have ever heard of John Pappajohn, 69, of Des Moines, Iowa. He has received no press outside his home state, but his investment acumen is the stuff of legend. When he set up shop as a venture capitalist in 1969, he had $100,000. By investing that money in health care startups he has turned it into a personal fortune of more than $200 million.