Insmed Inc (INSM)

[wjlknew]

A concise description of ALS and the Phase III trial of Myotrophin (Cephalon) can be found at:

http://serendip.brynmawr.edu/bb/neuro/neuro99/web1/Rodrigo.html

Apparently Myotrophin IGF-1 is thought to be a possible treatment to delay the progression of the disease and prolong useful life. It IS NOT expected to be a cure. The drug received an approvable letter from the FDA in 1998 or 1999, if an additional Phase III trial was conducted. That trial is complete, but results are not expected until later this year. That probably explains Mr. Bruno's treatment with IGF-1 in 2003 ... which he followed up by treatment with Iplex beginning in 2004.

Mr. Bruno's experience has raised a lot of hope for a "cure" for ALS. Logic would suggest that if naked IGF-1 delays the effects of the disease, then Iplex may delay it more due to its more effective use of IGF-1. Hopefully that is the case, but to speculate about a "cure" is not justified at this juncture.

You are not even suggesting a "cure". I only use your post as a chance to expand on Mr. Bruno's testimonial.