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Friday, July 12, 2024 2:52:27 PM
"number of pills" means nothing unless you standardize the amount of oxy in each pill. Let's assume the pills were 5-325 (5mg oxy, 325 mg acetaminophen). That's the standard opioid pill given to outpatients.
#3 (first seven days) results:
Active group: 59 patients, Mean = 21 mg
Placebo group: 60 patients, Mean = 17 mg
Active group took an average of 4.2 pills each in the first seven days
Placebo group took an average of 3.4 pills each in the first seven days
That's less than one pill per day avg in each group. What Ilfeld was looking for, though, was something more like the Active Group taking only one pill each in seven days while the placebo group took 3 or 4 pills each. That didn't happen. Ilfeld might offer a hypothesis WHY if he publishes this. He might offer an outlier explanation like Koneru did, but if the protocol doesn't specify beforehand that he would remove outliers, he can't remove them now.
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