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ViroPharma Inc.'s (VPHM) fourth-quarter net income fell to $18 million, or 25 cents a share, from $72.7 million, or $1.17 a share, a year ago, due in part to a change in income tax accounting.

A Thomson Financial survey of analysts, on average, predicted earnings of 20 cents a share for the quarter. Analysts' estimates usually exclude items.

The Exton, Pa., pharmaceutical company's revenue fell 4.6% to $38.6 million from $40.5 million a year ago.

For 2007, the company expects net product sales of $195 million to $205 million.

-Veronica Dagher; 201-938-5400; [e-mail]

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(END) Dow Jones Newswires