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Tuesday, 06/18/2024 2:05:23 PM

Tuesday, June 18, 2024 2:05:23 PM

Post# of 463351
Notes from SHM stjernerogvann from ST-
SAVXL notes from today's ASM:
1. Paper due before MAA
2. MAA should come before end of SEP but could slide to YE
3. Cohort 1 referred to low dose Part A group in 3-71 schizophrenia trial - high dose cohort also accrued and dosed now. Part B coming up. Possible completion by YE.
4. PD and Rett trial should start this year.
5. Autophagy is key component of MOA
(Sigmar1 promotes autophagy, the recycling of underperforming or unhealthy cells)
6. They have not met with FDA since end of P2/p3 - plan to do so when they have OLE data/analysis and can show the same data that MAA has seen
If more occurs to me then I will add later.
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