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Re: Joseph_K post# 459232

Friday, 05/17/2024 11:01:50 AM

Friday, May 17, 2024 11:01:50 AM

Post# of 460245
Anavex Researchers Are At Work

Do you have any reason to believe Anavex has more such "stuff happening" than most other biotech companies?


Not likely. Anavex is not a big biotech. Doesn’t even have a revenue-generating drug yet

But it does have proprietary drug candidates for which it has expertise. On the company’s website those pipeline drugs are listed, along with the diseases they will target.

But, take into consideration Anavex’s list of scientific advisors:

Marwan N Sabbagh, MD
Jeffrey Cummings, MD
Prof. Dr. Timo Grimmer, MD
Norman Relkin, MD, PhD
Daniel Weintraub, MD
Andrew J. Cole, MD, FRCP(C)
John Harrison, PhD
Paul Aisen, MD
Dag Aarsland, MD, PhD
Jacqueline French, MD, FAAN
Corinne Lasmézas, PhD, DVM
Ottavio Arancio, MD, PhD
Tangui Nicolas Maurice, PhD

Do these medical research experts spend their time with Anavex merely twiddling their thumbs while meditating on how blarcamesine will fix Alzheimer’s? Or, might it be supposed, they actually devise and conduct new research on not only the drugs listed in Anavex’s pipeline webpage, but on a host of chemical variations of these and other related molecules?

Doubtless, with non-disclosure agreements, they have devised and arranged all sorts of drug research with new post-docs and contract research teams.

I’ve been there; done this myself. I am a recognized expert in one ecological problem area. I proposed a unique solution to a regional ecological problem. But, like Anavex’s sigma-1 receptor agonists, my proposals were utterly discounted and rejected. “Goofy idea. That can’t work.”

But, with my assembled team of researchers at a local university, we applied for and got a federal grant to try out my idea — a tiny ecological Phase 1 clinical (ecological) trial of the idea. And, as I predicted, the project actually did solve or significantly minimize the ecological problem it was aimed at. Like Anavex science, my idea was new, not in any textbook or observed by anyone. Just a private concept, based on my 50 years of professional work on the topic.

It worked. The project was small, merely a demonstration of the effective mechanics of the concept. Presently, my research team is going for a $5 million dollar grant to apply the concept regionally, to help solve a major ecological problem in my area. Like Anavex and the development of its drugs, implementation is a frustratingly slow process. But, in five to ten years, the innovative concepts I’ve devised will be in place. A specific ecological problem will be efficiently, effectively, solved; at minimal cost but with additional good ecological outcomes.

With Anavex, not only will CNS diseases be effectively treated, they will be prevented (the prophylaxis factor). In my case, not only will the targeted ecological problem be significantly reduced or minimized, there will be significant, other, good ecological outcomes.

These are the kinds of things good research teams do. I look forward, five to ten years, to see what emerges from Anavex research. Anavex thumbs are not being merely twiddled. Lots of “stuff” happening — unconstrained by legacy and textbook perspectives.
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