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Re: Nemesis18 post# 690743

Saturday, 05/11/2024 7:59:15 PM

Saturday, May 11, 2024 7:59:15 PM

Post# of 694366
Nice, but as you know or should know, this is irrelevant to do with dcvax-l at this time.

Dabrafenib (both as monotherapy and in combination with trametinib) has proven to be efficacious in the 7% of LGG patients who have the BRAF V600E mutation.

As you know, NWBO will run a pediatric clinical trial before it is possibly approved for children but dcvax-l is currently only targeted for glioblastoma ie grade 4 glioma, not the low grade gliomas, and not the small number of LGG with BRAF V600E that dabrafenib therapy targets.
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