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Re: georgejjl post# 458788

Saturday, 05/11/2024 9:25:22 AM

Saturday, May 11, 2024 9:25:22 AM

Post# of 459967
GOOD NEWS starting to flow from new sources...nice to see...C'MON... show (. FDA SPEAK. "Proven by provision of objective evidence", ) showing us the way to get started REALLY making news..."Before vs After images are killer proof, even W/S & FDA can't screw THAT UP".

The European Union is currently working with Anavex to examine Blarcamesine’s clinical trial results and other factors for possible approval for use in combating Alzheimer’s Disease.

The U.S. FDA currently is not evaluating Blarcamesine for approval in the United States.

Today, Anavex Life Sciences CEO Christopher Missling discussed data from the Phase 2b/3 drug trial of Blarcamesine showing that the drug lowered the level of beta amyloid plaques in the brains of Alzheimer’s patients. This result was actually somewhat surprising, as, according to Dr. Missling Blarcamesine is designed to alter brain chemistry upstream from the production of beta-amyloid.

Unlike Biogen’s Lecanemab, Blarcamesine is not designed to clear beta-amyloid plaques from the brain.

The implication seems to be that Blarcamesine, working upstream, prevents the production of these plaques rather than clearing them out.

Another possible implication is that Blarcamesine helps the brain with autophagy — regulating itself and recycling cell parts. Dr. Missling has noted in the past that the drug is designed to help with autophagy.

Through autophagy, then, the brain may be clearing the plaques on its own, as spurred on by Blarcamesine.

In the conference call, Dr. Missling also noted that the drug trial demonstrated that Blarcamesine prevents brain shrinkage among Alzheimer’s patients. In fact, in my reading of the results, this was perhaps the most statistically significant finding of the entire drug trial.

When I say “brain shrinkage” I mean the loss of brain mass: losing millions of brain cells. I have seen this loss in my mother’s brain scans; my mother suffers from Alzheimer’s Disease.

Could the preservation of brain mass be an effect of the autophagy that



BREAKING: Anavex’s Blarcamesine reduces plaque in Alzheimer’s brains without dangerous side effects

From ST

https://medium.com/@irwinbooks/breaking-anavexs-blarcamesine-reduces-plaque-in-alzheimer-s-brains-without-dangerous-side-effects-df893e362a37

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