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Re: H2R post# 689818

Wednesday, 05/08/2024 6:38:14 PM

Wednesday, May 08, 2024 6:38:14 PM

Post# of 694828
Below is a post that I wrote back when the Nature article was pre-released re: the results.

I'm linking it again below as it's very helpful, IMO, as a synopsis of the results of the GBM patients.
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=172833579&txt2find=methylated

To me, the first stat to note is that the GBM patient who lived the longest in this trial was a methylated patient on PLACEBO only - so JUST DCVax-L.

Next, out of the 5 GBM patients on Poly ICLC, the mOS was 28.6 months - and that median was an UNMETHYLATED GBM patient.

So, IMO, when you add in the Poly ICLC, it looks like the unmethylated GBM patients now have a legitimate shot at turning unmethylated GBM into, minimally, at least a chronic disease that can be treated over and over when the tumor returns.
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