Amarin Corp Plc (AMRN)

[CaptBeer]

One of the big sticking points for the German G-BA was their clinical assessment of the outcomes of the REDUCE-IT trial and their interpretation of the "Level of Evidence" regarding "bias" in those outcomes. IMO, they placed far too much scrutiny on the mineral oil placebo as a contradictor of high-quality evidence while ignoring other biasing risk factors.

For example: The Gold Standard for assessing the risk of bias in randomized clinical trails (RCT's), is the "Cochrane Risk of Bias Assessment Tool." This Tool rates 7 bias risk factors as either Low, High or unclear. The 7 bias risk factors are:
Randomization, Allocation concealment, Participants & personnel, Outcome assessment, Selective Outcome reporting, Incomplete outcome data, and Other.

The REDUCE-IT Trial rated a "Low Risk of bias" in each category. The mineral oil hoax would fall under the "Outcome assessment" category. Furthermore, new data is continuing a steady stream of Evidence Based Medicine (#EBM) that IMO, completely debunks the mineral oil conspiracy. Germany, France and Italy need to get their shit together before MACE gets out of control in their countries.