Amarin Corp Plc (AMRN)

[Tatsumaki]

and THERE IS NO PRIOR ART of E-EPA

Every single thing Amarin has ever done has been based on Mochida's prior art. Epadel (E-EPA) was first marketed in Japan in 1990. Yes, it's been around that long. Reduce It was based on Jelis (proved CVD benefit in Japan) and only done because FDA said they needed to do a study that represented western diets and couldnt use Jelis for that data.

All Amarin has EVER done is find a product in another country and bring it to different markets. Same thing with LR EtEPA. It's just Mochida's MND-2119 brought to other markets under license. Also why Amarin doesnt have a pipeline for a future, they dont really develop anything on their own.

The only reason they used E-EPA is Tg forms of omega 3s supplements were already on the market in the US and Tg forms could not qualify as a drug. FDA will not approve converting an existing food/supplement on the market to drug status. But they had an opening with E-EPA. Same reason Lovaza is ethylated Om3 mixture and got approval. As many have said, Tg has much better bioavailability, so the best thing would have been to use re-esterified EPA triglyceride (rTG) but nobody can because Tgs are just supplements in the US.