NorthWest Biotherapeutics Inc (NWBO)

[skitahoe]

I think that question is particularly relevant to patients with brain cancers who've already had their cancer properly preserved in anticipation of an approval of the vaccine. I've got to believe the company has some indication of the size of this group, but I'd suspect that some have been waiting for many months if they couldn't afford the compassionate use program. I don't know if the backlog is in the tens, hundreds, or thousands, but I suspect it's substantial. We'll probably never know, nor will we know how many people here, or elsewhere are in the same position, essentially praying for approval while the vaccine may still do them some good.

I believe that Sawston will be at maximum manual capacity essentially as soon as they have approval and patients are lined up for leukapheresis so the vaccine can be made. As I understand it, they want the leukapheresis to be fresh, while the tumor may have been cryogenically frozen a substantial period ago. The vaccine would essentially constitute what the patient is fighting right at the time the leukapheresis is done.

Next Monday will essentially be day 120, their new goal in the UK, I don't believe they report new approvals that day, but if notified of approval, I believe the company can announce it immediately. Whether it's then, or 30 days later, by day 150, it's getting closer and barring a delay we'll be a very different company when it happens.

Gary