Excellent news 🗞️
Amidst overt rampant corruption and stock manipulation, $TSOI calmly reports Patent issuance for QM+Metformin.
USPTO validated. Again. 🤓
It’s amazing how TSOI IP just seems to flow effortlessly from the germination station.
Heres a bit from the Issued Patent:
“Who knew Metformin would supercharge QuadraMune? Well, in short, we did.
Claims
1. A method of augmenting natural killer cell activity in a mammal suffering from COVID-19, comprising administration to said mammal a therapeutic combination comprising of: a) Green Tea and/or extract thereof; b) Blueberry and/or extract thereof; c) Nigella sativa and/or extract thereof; d) broccoli and/or extract thereof and e) metformin.
2. The method of claim 1, wherein said green tea extract is epigallocatechin-3-gallate or an analogue thereof.
3. The method of claim 1, wherein said blueberry extract is pterostilbene or an analogue thereof.
4. The method of claim 1, wherein said Nigella sativa extract is thymoquinone or an analogue thereof.
5. The method of claim 1, wherein said broccoli extract is sulforaphane or an analogue thereof.
6. The method of claim 1, wherein said therapeutic combination is administered at a dosage and frequency sufficient to stimulate NK activity in a host.
7. The method of claim 6, wherein NK activity is production of IL-18.
8. The method of claim 7, wherein said natural killer cell activity is quantified by ability to lyse a virally infected cell.
9. The method of claim 7, wherein said natural killer cell activity is quantified by ability to lyse K562 cells.
10. The method of claim 7, wherein said natural killer cell activity is quantified by ability to lyse YAC-1 cells.
11. The method of claim 6, wherein stimulation of NK cell activity is production of VEGF.
12. The method of claim 6, wherein stimulation of NK cell activity is production of FGF-1.
13. The method of claim 12, wherein said NK cell activation is induction of T helper cell 1 activity.
14. The method of claim 13, wherein said NK cell activation comprises production of granzyme.
15. The method of claim 12, wherein said NK cell activation is capable of induction of T cytotoxic cell activity.
16. The method of claim 1, wherein said therapeutic combination is administered at a dosage and frequency sufficient to stimulate NK cell stimulation.
(33) 24 healthy volunteers were randomized to receive placebo or QuadraMune for 1 week. Another 24 diabetics taking metformin were randomized to receive metformin and placebo or metformin and QuadraMune. Blood was taken at one week post study initiation and assessment of NK activity was performed by assessment of NK lysis. As seen below, an increase in NK activity was seen in healthy controls taking QuadraMune. Additionally, metformin synergized with QuadraMune to stimulate potent NK cytotoxicity towards K562 cells. Results are shown in FIG. 1.
$.0008, isn’t that something.
Right back where I started, darn near.
Yet, the company has expanded exponentially.
Food for thought.
Bullish
