I'm listening to at least the beginning of the presentation, but doubt I'll listen to the entire 3 hour presentation. The one thing I found very interesting is that with all T-cells coming from the Thymus, and capacity normally diminishing with age, what is it that our vaccine is doing that suddenly increases T-cell levels in the tumor. Is the Thymus producing dramatically more, which sounds like a big positive, or are the T-cells normally found in the body somehow being concentrated in the tumor, another positive when it comes to curing cancer, but not as big as if the Thymus is suddenly greatly increasing its production. Over time T-cells are needed throughout the body, so we need to not diminish them too much everywhere else.
I don't know if Dr. Bosch, or anyone else who discovered the dramatically higher T-cell counts in the tumor have determined if they're there because of dramatically increased production in the Thymus. If this is the case, and if making DCVax-Direct can cause the same reaction, even if not injected into a cancer, say into fatty tissue, if T-cell production increased, it truly could be beneficial in many diseases beyond solid cancers, and perhaps in blood borne cancers as well. I know CAR-T, or modified T-cells have been used at City of Hope for many years, I met a patient who received his own T-cells modified with a disabled HIV virus 3 days after I had my stem cell transplant. He actually got his own stem cells the day I received mine, then the modified T-cells 3 days later. When I happened to meet him, about 2 months after the transplant, he was coming in every couple weeks, while I was coming in twice a week. The reason was he received his own cells, while mine were from a donor, in his case, rejection wasn't a problem. I still have dermatological issues as a minor problem caused by the DNA difference even though I had a 12 point match, which is as good as it gets.
As you all know, I'm not an expert in the medical feel, I'm purely looking at this as a layman, but I'm curious what others here may think, or if you actually know that our vaccine is spurring T-cell production in the Thymus of people of all ages that the vaccine is being given to.
Gary
