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georgejjl

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georgejjl

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Sunday, 03/17/2024 7:21:14 PM

Sunday, March 17, 2024 7:21:14 PM

Post# of 473031

McGill-APP homozygous Tg rats (n = 22) express the human APP751 gene carrying the Swedish and the Indiana mutations under the control of the murine Thy1.2 promoter (Flores-Aguilar et al., 2022, Iulita et al., 2014, Leon et al., 2010, Wilson et al., 2016). Age-matched wild-type (wt) littermates rats (n = 22), derived from the same breeding scheme (heterozygous × heterozygous), were used as controls.



These a specially bred rats for the purpose of testing human drugs in animals prior to the same drugs used in humans.

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