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Friday, March 08, 2024 5:50:52 PM
“The greatest strides in therapeutic vaccine research have been in the treatment of cancer.”
Of the three vaccines approved for use in the United States, two are used to treat advanced cancer that has spread to distant parts of the body (metastatic disease), while the other is used to prevent the progression of carcinoma in situ (a precancer condition).
The approved vaccines, from oldest to newest, are:
Tice (Bacillus Calmette-Guerin): A live-attenuated vaccine approved in 1990 for the treatment of carcinoma in situ of the bladder7
Provenge (sipuleucel-T): A dendritic cell-based vaccine approved in 2010 that is used for the treatment of metastatic, hormone-resistant prostate cancer8
Imlygic (talimogene laherparepvec): A live-attenuated vaccine approved in 2015 that is indicated for the treatment of advanced oncolytic melanoma (a type of skin cancer)9
https://www.verywellhealth.com/what-is-a-therapeutic-vaccine-3133276
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