Anavex Life Sciences Corp (AVXL)

[frrol]

Anavex has not made "claimed benefits of better sleep, reduced blood pressure, improved tau levels" in our AD 2b/3 results. In the paper, we will very likely see the results for the latter, and may see results for the first two. They are most likely not stat-sig, as with ADL (and possibly even no discernible effect). The CSF pTau results will be considered in regulatory evaluations.

Not stat-sig would be unfortunate, though it would not rule out an approval. It just makes it less likely than otherwise. If pTau levels don't credibly drop, it will be helpful to have a plausible clinical explanation.