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Re: Arby2000 post# 676733

Wednesday, 03/06/2024 2:34:22 PM

Wednesday, March 06, 2024 2:34:22 PM

Post# of 700013

The first sentence says '...histology consistent with glioblastoma'. The rest of the document snippet raises the issue of a possible misdiagnosis and as you said, there is no connection to NWBO's DCVAX-L or the trial.


Agreed.

The possibility of a misdiagnosis is very real as the shift from histological to genetic definitions was just firming up at that time.

It reads to me like he screened for the -L trial thinking he had true GBM. Then found out later it was IDH-mutant and with the full resection he was doing quite well so dropped out.

Unless there is more information I fail to see how that implies anything wrongful on NWBO's (or Ashkan's ) side Maybe he really was overtreated with Tez (being IDH-M and unmeth). But that would have been the same regardless of any NWBO trial.
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