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DewDiligence

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DewDiligence

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Re: dewophile post# 2884

Wednesday, 03/06/2024 12:08:42 PM

Wednesday, March 06, 2024 12:08:42 PM

Post# of 3017

[THRD] had 2 cases of DILI (drug induced liver injury) in their first 3 patients! They think they have identified the metabolite causing this and are hopeful.

Ouch!

I'm getting more excited about this area for ENTA if they can get a good compound. Liver tox is tough to predict preclinically (THLD acknowledged this), so the phase 1 next year is going to be quite meaningful (especially with a good biomarker of activity to go along w safety).

If I were a baseball manager, I would say ENTA was overdue for a successful at-bat, LOL.

“The efficient-market hypothesis may be
the foremost piece of B.S. ever promulgated
in any area of human knowledge!”

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